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Endocrine Abstracts

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ea0073oc3.6 | Oral Communications 3: Pituitary and Neuroendocrinology | ECE2021

Expression and possible role of integrins in corticotroph tumours

Chen Xiao , Simon Julia , Luis Perez-Rivas , Jörg Flitsch , Honegger Jürgen , Rachinger Walter , Stalla Günter , Reincke Martin , Theodoropoulou Marily

IntroductionIntegrins are heterodimeric transmembrane proteins composed of alpha and beta subunits that mediate cell-cell and cell-extracellular matrix (ECM) interactions. Several integrins are overexpressed in human cancers and their ECM recognition motif, arginine-glycine-aspartate (RGD), is being utilized for tumour imaging and targeting.AimTo explore the expression and function of RGD-binding integrins in...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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